By Morton I. Grossman
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Extra info for Cellular Basis of Chemical Messengers in the Digestive System
That a CNS localizations of these opiate peptides is a phylogenetically old feature is supported also by the preliminary results of immunohistochemical studies in hoverfly larva (11). Using an antiserum raised against a mixture of synthetic human Met- and Leu-enkephalins and one against synthetic human /3-endorphin, groups of immunoreactive cells occurred in the pars intercerebralis region. Whether or not one and the same cell stored both enkephalin and /3-endorphin—as described for other G E P neurohormones (27)—is still not known.
Brew, Η. Faber, and V. ). Miami Winter Symposium Series, Vol. 16. Academic Press, N e w York, 1979:361-378. Dockray, G. , Vaillant, C , and Hutchison, J. , Immunochemical characterization of peptides in endocrine cells and nerves with particular reference to gastrin and cholecystokinin. In: University of California Los Angeles Forum in Medical Sciences. This volume. , and Dubois, Μ. P;, Cells reacting with a somatostatin an tiserum in the pars intercerebralis of an insect, Locusta migratoria. C.
1979, 11:589-606. 28. , Peptidergic system of the gastrointestinal tract. Verhandl. Dtsch. Ges. Inn. , 1979, 85:1525-1534. 29. Kramer, K. , Speirs, R. D . , and Child, C. N . , Immunochemical evidence for a gastrinlike peptide in insect neuroendocrine system. Gen. Comp. , 1977, 32:423426. 30. -L, and Rehfeld, J. E . , Characterization of antral gastrin cells with regionspecific antisera. / . Histochem. , 1977, 12:1317-1321. 31. , Identification of a lobe in the adult human pancreas rich in pancreatic polypeptide.
Cellular Basis of Chemical Messengers in the Digestive System by Morton I. Grossman