Natural Killer Cells by Eric Vivier, James Di Santo, Alessandro Moretta (eds.) PDF

By Eric Vivier, James Di Santo, Alessandro Moretta (eds.)

ISBN-10: 3319239155

ISBN-13: 9783319239156

ISBN-10: 3319239163

ISBN-13: 9783319239163

To have a good time the fortieth anniversary of the invention of typical Killer (NK) cells, this quantity makes a speciality of the new advances in our figuring out of NK mobile improvement and differentiation and their acquisition of useful houses, in addition to the most recent versions for NK-cell research in mice and functions in scientific medication. NK cells have travelled a circuitous direction from their preliminary description as ‘spontaneous killers’ (for a few easily an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of motion in immune security and a major mediator of immune reactivity in wellbeing and fitness and sickness. jointly, those reports offer a well timed and concise photo of the evolution of NK cells as crucial brokers in immunity and as effective guns opposed to affliction. This publication deals an attractive and insightful source for scientists and clinicians.

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Natural Killer Cells - download pdf or read online

To rejoice the fortieth anniversary of the invention of traditional Killer (NK) cells, this quantity specializes in the new advances in our figuring out of NK mobilephone improvement and differentiation and their acquisition of useful homes, in addition to the newest types for NK-cell research in mice and functions in scientific medication.

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Annu Rev Immunol 32:403–432 Sun XH (1994) Constitutive expression of the Id1 gene impairs mouse B cell development. Cell 79:893–900 Sun JC (2010) Re-educating natural killer cells. J Exp Med 207:2049–2052 Sun JC, Lanier LL (2011a) Natural Killer cell response against viruses. In: Kaufmann S, Rouse B, Sacks D (eds) The immune response to infection. , pp 197–207 Sun JC, Lanier LL (2011b) NK cell development, homeostasis and function: parallels with CD8(+) T cells. Nat Rev Immunol 11:645–657 Sun JC, Ma A, Lanier LL (2009) Cutting edge: IL-15-independent NK cell response to mouse cytomegalovirus infection.

1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J Exp Med 201:1487–1502 Daussy C, Faure F, Mayol K, Viel S, Gasteiger G, Charrier E, Bienvenu J, Henry T, Debien E, Hasan UA et al (2014) T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. J Exp Med 211:563–577 De Obaldia ME, Bhandoola A (2015) Transcriptional regulation of innate and adaptive lymphocyte lineages. Annu Rev Immunol 33:607–642 DeHart SL, Heikens MJ, Tsai S (2005) Jagged2 promotes the development of natural killer cells and the establishment of functional natural killer cell lines.

Immunity 9:543–553 Weber BN, Chi AW, Chavez A, Yashiro-Ohtani Y, Yang Q, Shestova O, Bhandoola A (2011) A critical role for TCF-1 in T-lineage specification and differentiation. Nature 476:63–68 Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH (2008) T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol 180:8004–8010 Wheeler JC, Shigesada K, Gergen JP, Ito Y (2000) Mechanisms of transcriptional regulation by Runt domain proteins. Semin Cell Dev Biol 11:369–375 Wilkinson B, Chen JY, Han P, Rufner KM, Goularte OD, Kaye J (2002) TOX: an HMG box protein implicated in the regulation of thymocyte selection.

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Natural Killer Cells by Eric Vivier, James Di Santo, Alessandro Moretta (eds.)

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